Patent · US Expired

Process and solvate of 2-methyl-thieno-benzodiazepine

US5631250A · kind A · utility

19Cited by
9References
10Claims
0Family size

Assignees

Inventors

Key dates

Filing dateMar 24, 1995
Grant dateMay 20, 1997
Priority date
Expiry dateMar 24, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D495/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention provides lower alcohol solvates of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine (olanzapine) and a process for making such lower alcohol solyates of olanzapine. The invention provides a method for using such solyates of olanzapine to prepare substantially pure anhydrous Form I 2-methyl-thieno-benzodiazepine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.