Quinolone carboxylic acid derivatives and process for preparing the same
US5631266A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 7, 1995 |
| Grant date | May 20, 1997 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to quinolone carboxylic acid derivatives having useful antibacterial activities of formula (I): ##STR1## wherein, R.sub.1, R.sub.2, and R.sub.3, which may be the same or different, are each hydrogen or a halogen atom, or a lower alkyl group optionally substituted with an amino or a hydroxy group; PA1 R.sub.4 is hydrogen atom, a lower alkyl, benzyl, t-butoxycarbonyl or ethoxycarbonyl group; PA1 R.sub.5 is hydrogen, chlorine atom, methyl or an amino group; PA1 R.sub.6 is a lower alkyl group, or a cyclopropyl or a phenyl group optionally substituted with a halogen atom; and PA1 X is nitrogen atom, or a methyne group optionally substituted with a lower alkyl or a lower alkoxy group or a halogen atom, and pharmaceutically acceptable salts thereof, and processes for preparing these compounds. The present invention also relates to novel intermediates which are useful for preparing the quinolone compounds of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.