Patent · US Expired

Labelled boronic acid derivatives

US5631364A · kind A · utility

21Cited by

3References

17Claims

0Family size

Assignee

Axis Biochemicals ASA · NO

Inventors

Erling Sundrehagen · Oslo, NO
Frank Frantzen · Oslo, NO

Key dates

Filing date	Mar 31, 1994
Grant date	May 20, 1997
Priority date	—
Expiry date	Mar 31, 2014

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/25375
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention provides novel labelled boronic acid conjugates of formula ##STR1## (wherein V is a reporter moiety; W.sup.2 is a bond or an organic linker moiety; PA1 W.sup.1 is a *SO.sub.2 NR.sup.2, *CON.sup.2 or *CH.sub.2 N.sym.R.sup.2 .sub.2 group bound at the *-marked atom to the phenyl ring; PA1 R.sup.1 is hydrogen or an electron withdrawing substituent group; and each R.sup.2 independently is hydrogen or an optionally hydroxylated and optionally C.sub.1-6 -alkoxylated C.sub.1-6 -alkyl group) and salts thereof, e.g. for use in assays for cis-diols such as glycated blood proteins, having enhanced water-solubility and storage stability.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.