Patent · US Expired

Optically-active isomers of dideoxycarbocyclic nucleosides

US5631370A · kind A · utility

3Cited by
6References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 15, 1994
Grant dateMay 20, 1997
Priority date
Expiry dateAug 15, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D473/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A therapeutic method is provided, employing an antiviral compound of the general formula: ##STR1## wherein Z is H, OR' or N(R).sub.2, wherein R' is H, (C.sub.1 -C.sub.4)alkyl, aryl, CHO, (C.sub.1 -C.sub.16)alkanoyl or O.dbd.P(OH).sub.2, Y is CH or N, and X is selected from the group consisting of H, N(R).sub.2, SR, OR' or halogen, wherein R is H, lower(C.sub.1 -C.sub.4)alkyl, aryl or mixtures thereof, and the pharmaceutically acceptable salts thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.