Process for the preparation of ethyl 3S-[[4-[[4-(aminoiminomethyl)phenyl]amino]-1,4-dioxobutyl]amino]-4-penty noate

US5631399A · kind A · utility

Assignee

• G.D. Searle LLC · US

Inventors

• Kevin A. Babiak · Evanston, US
• Srinivasan Babu · San Diego, US
• James R. Behling · Lindenhurst, US
• Mark Laurence Boys · Lyons, US
• Kimberly J. Cain-Janicki · Sleepy Hollow, US
• Wendel W. Doubleday · New Richmond, US
• Payman Farid · Deerfield, US
• Timothy J. Hagen · Gurnee, US
• E. Ann Hallinan · Evanston, US
• Donald W. Hansen, Jr. · Chicago, US
• Donald E. Korte · Mundelein, US
• Kathleen T. Mc Laughlin · Arlington Heights, US
• John R. Medich · Highland Park, US
• Sean T. Nugent · Grayslake, US
• Vlasdislav Orlovski · Buffalo Grove, US
• Jung Min Park · San Francisco, US
• Karen B. Peterson · Vernon Hills, US
• Daniel R. Pilipauskas · Glenview, US
• Barnett S. Pitzele · Skokie, US
• Sofya Tsymbalov · Skokie, US
• Glenn L. Stahl · Bradley, US

Key dates

• Filing date: May 14, 1996
• Grant date: May 20, 1997
• Expiry date: May 14, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C257/18
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a novel process for the preparation of ethyl 3S-[[4-[[4-(aminoiminomethyl)phenyl]amino]-1,4-dioxobutyl]amino]-4-pentyno ate and pharmaceutically acceptable acid addition salt thereof.