Polypeptide inhibitors of gamma interferon
US5632988A · kind A · utility
10Cited by
4References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 7, 1992 |
| Grant date | May 27, 1997 |
| Priority date | — |
| Expiry date | Apr 7, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K7/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel synthetic polypeptides comprising the amino acid subsequence Arg-Arg-Lys-Trp-Gln are provided by this invention. Also provided are methods for the use of such polypeptides, other known polypeptides containing such subsequence and a variety of acidic or basic polypeptides and proteins as inhibitors of the binding of gamma interferon to its cellular receptors. The methods of this invention are potentially applicable to the treatment of pathological conditions believed to be mediated by gamma interferon, such as autoimmune disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.