Buffer system for increasing seroconversion efficiency
US5633130A · kind A · utility
11Cited by
5References
7Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 8, 1994 |
| Grant date | May 27, 1997 |
| Priority date | — |
| Expiry date | Sep 8, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of increasing efficiency of deantigenation of blood group epitopes on erythrocytes (seroconversion) by exoglycosidases utilizing a step of performing the deantigenation in a zwitterionic buffer. The method provides a buffer system and exoglycosidase that utilizes a twenty to one hundred fold lower total enzyme mass than the prior art methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.