Patent · US Expired

Indoline derivatives, method of preparation and use

US5633276A · kind A · utility

12Cited by
2References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 14, 1996
Grant dateMay 27, 1997
Priority date
Expiry dateJun 14, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A compound of formula (I) ##STR1## wherein, R.sup.1 is hydrogen, halogen or C.sub.1-6 alkyl; PA0 R.sup.2 is a group of formula --CR.sup.3 R.sup.4 (CH.sub.2).sub.p NR.sup.5 COR.sup.6 ; PA0 R.sup.3, R.sup.4 and R.sup.5, which may be the same or different, are hydrogen or C.sub.l-6 alkyl; PA0 R.sup.6 is C.sub.1-6 alkyl or C.sub.3-7 cycloalkyl; PA0 n is an integer of 2, 3 or 4; PA0 p is an integer of 1, 2, 3 or 4; and pharmaceutically acceptable salts and solvates thereof. A compound of formula (I) is useful in the treatment of conditions associated with a disturbed functioning of the melatonin system.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.