Phosphoramidite derivatives of texaphyrins
US5633354A · kind A · utility
7Cited by
29References
18Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Mar 13, 1996 |
| Grant date | May 27, 1997 |
| Priority date | — |
| Expiry date | Mar 13, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/546
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is directed to a method of incorporating expanded porphyrins, and particularly of incorporating a sapphyrin or a texaphyrin, before, during, or after chemical synthesis of an oligomer to form an expanded porphyrin-oligonucleotide conjugate, and particularly a sapphyrin- or texaphyrin-oligonucleotide conjugate. This method includes reacting derivatized nucleotides and a sapphyrin or a texaphyrin in a desired order in an automated or manual DNA synthesizer having a solid support to form a sapphyrin- or a texaphyrin-oligonucleotide conjugate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.