(Z,Z), (Z,E) and (E,Z) isomers of substituted bis(phenylmethylene)cycloketones
US5633381A · kind A · utility
24Cited by
2References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 5, 1994 |
| Grant date | May 27, 1997 |
| Priority date | — |
| Expiry date | Jul 5, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D335/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to novel (Z,Z), (Z,E) and (E,Z) olefin isomers of substituted benzylidene cycloketones and their pharmaceutically acceptable salts. The compounds of the invention are potent factor Xa inhibitors thereby acting as anticoagulants useful in a number of thrombotic disease states. Pharmaceutical compositions are proposed for the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.