Compositions and methods for the detection, quantitation and purification of antigen-specific T cells
US5635363A · kind A · utility
121Cited by
4References
16Claims
0Family size
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Key dates
| Filing date | Feb 28, 1995 |
| Grant date | Jun 3, 1997 |
| Priority date | — |
| Expiry date | Feb 28, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/868
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
T cells are specifically labeled according to their antigen receptor by binding of a multimeric binding complex. The complex is prepared with major histocompatibility complex protein subunits having a homogeneous population of peptides bound in the antigen presentation site. The multimeric MHC-antigen complex forms a stable structure with T cells, thereby allowing for the labeling, identification and separation of specific T cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.