Yeast strains with stable integration of heterologous genes
US5635369A · kind A · utility
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16Claims
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Key dates
| Filing date | Jan 13, 1994 |
| Grant date | Jun 3, 1997 |
| Priority date | — |
| Expiry date | Jan 13, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/81
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Yeast strains and a method of expression in yeast of the monooxygenase activity of heterologous cytochromes P450 are disclosed. Within the genome of the yeast strain, genes for NADPH-cytochrome P450 reductase and cytochrome b5 are stably integrated and coexpressed. The genome is transformed with a plasmid carrying a cassette for the expression of a heterologous P450 gene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.