Carboxylic acid compound having condensed ring, salt thereof and pharmaceutical use thereof
US5635527A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 6, 1996 |
| Grant date | Jun 3, 1997 |
| Priority date | — |
| Expiry date | Feb 6, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/68
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A novel carboxylic acid compound having a condensed ring, which is represented by the formula (I) ##STR1## wherein each symbol is as defined in the specification, a pharmacologically acceptable salt thereof, a pharmaceutical composition thereof and pharmaceutical use thereof. The novel carboxylic acid compound having a condensed ring and pharmacologically acceptable salt thereof of the present invention have superior GPIIb/IIIa antagonism in mammals inclusive of human; can be administered orally; have long life in blood and low toxicity; and show less side-effects. Accordingly, they are extremely useful for the prophylaxis and treatment of thrombotic diseases and other diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.