Sulfonamidodioxepanes, methods of preparation, intermediates, salts and use thereof

US5635529A · kind A · utility

Assignee

• PLIVA, farmaceutska, kemijska, prehrambena i kozmeticka industrija, dionicko drustvo · HR

Inventors

• Miljenko Dumic · Zagreb, HR
• Darko Filic · Zagreb, HR
• Mladen Vinkovic · Čakovec, HR
• Blanka Jamnicky · Zagreb, HR

Key dates

• Filing date: Feb 17, 1995
• Grant date: Jun 3, 1997
• Expiry date: Feb 17, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P3/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel O-substituted or O-unsubstituted 6-sulfonamido-1,3-dioxepane-5-ols having hypoglycemic activity are obtained from 6-amino-1,3-dioxepane-5-ol, tetrahydro-6H-[1,3]-dioxepino[5,6-d]oxazole, 5,6-epoxy-1,3-dioxepane or N-sulfonyl-tetrahydro-1H,4H-[1,3]-dioxepino[5,6-b]azirine as starting materials.