Fluorocarbon emulsions with reduced pulmonary gas-trapping properties
US5635538A · kind A · utility
14Cited by
11References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 16, 1993 |
| Grant date | Jun 3, 1997 |
| Priority date | — |
| Expiry date | Mar 16, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0026
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A fluorocarbon emulsion which exhibits reduced pulmonary gas-trapping properties in species-sensitive laboratory animals is disclosed. Additionally, the fluorocarbon component(s) exhibit short organ retention time(s). The emulsion includes an aqueous phase, an emulsifier, and a fluorocarbon (or fluorocarbon composition), having a vapor pressure of less than about 8 torr to reduce pulmonary gas-trapping, and having an organ retention half life of less than about 6 weeks and more preferably less than about 3 to 4 weeks.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.