Patent · US Expired

.alpha.-carboxy caged compounds

US5635608A · kind A · utility

53Cited by
2References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 8, 1994
Grant dateJun 3, 1997
Priority date
Expiry dateNov 8, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/07
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to caged compounds for the study of biological processes, where the caged compound has a photoremoveable .alpha.-carboxy-substituted o-nitrobenzyl group. Covalent attachment of the substituted o-nitrobenzyl to a parent compound yields a caged compound with biological and/or physical properties that are significantly altered from the original properties of the parent compound. Illumination of the caged compounds to cleave the photoremoveable group yields the parent compound with its original properties restored.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.