Composition for the sustained and controlled release of medicamentous substances and a process for preparing the same
US5637568A · kind A · utility
18Cited by
13References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 16, 1994 |
| Grant date | Jun 10, 1997 |
| Priority date | — |
| Expiry date | Mar 16, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K7/23
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition designed for the sustained and controlled release of medicamentous peptide substances having the formula (I): EQU Ac-D-Nal-D-pClPhe-R.sup.3 -Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH.sub.2 wherein R.sup.3 is D-Pal or D-Trp. The composition is obtained in the form of microspheres of a biodegradable polymeric material incorporating a water-insoluble salt of the peptide of formula (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.