Patent · US Expired

15-deoxyspergualin analogs, their method of preparation and their use in therapeutics

US5637613A · kind A · utility

2Cited by
0References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 23, 1995
Grant dateJun 10, 1997
Priority date
Expiry dateFeb 23, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates, by way of novel industrial products, to compounds which are structurally related to 15-deoxyspergualin and which have the formula ##STR1## in which: A is a single bond, a group --CH.sub.2 --, a group --CH.sub.2 O--, a group --CH.sub.2 NH--, a group --CH(OH)--, a group --CHF-- or a group --CH(OCH.sub.3)--, and PA1 n is equal to 6 or 8, and their addition salts. These novel compounds are useful especially as immunosuppressants. The invention further relates to the method of preparing said compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.