Structure based design of capsid stabilizing or antiviral agents
US5637708A · kind A · utility
2Cited by
7References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 2, 1995 |
| Grant date | Jun 10, 1997 |
| Priority date | — |
| Expiry date | Jun 2, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Agents having the structure, EQU U--CH.sub.2 --V--CH.sub.2 --W, and agents having the structure, EQU U--CH.sub.2 --V--CH.sub.2 --W--X--Y--Z, where U, W, and Z are double fused aromatic rings, V is a single six-membered aromatic ring with a hydroxyl group constituent, X is a polar group, and Y is a positively charged group, are disclosed. The double fused aromatic rings can be a five-membered aromatic ring, or a six-membered aromatic ring, fused to a six-membered aromatic ring; the double fused aromatic rings can comprise heteroatoms. The agents can be used as capsid stabilizing or antiviral agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.