Process for the preparation of 2,2-difluorobenzo[1.3]dioxolecarbaldehydes

US5637737A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Peter Andres · Ginsheim-Gustavsburg, DE
• Albrecht Marhold · Leverkusen, DE

Key dates

• Filing date: Aug 14, 1996
• Grant date: Jun 10, 1997
• Expiry date: Aug 14, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D317/46
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

2,2-Difluorobenzo[1.3]dioxole-carbaldehydes are prepared in a particularly advantageous manner if methylbenzo[1.3]dioxoles are chlorinated, the resulting dichloromethyl-2,2-dichlorobenzo[1.3]dioxole is fluorinated with hydrogen fluoride and the dichloromethyl-2,2-difluorobenzo[1.3]dioxole obtained by this procedure is reacted with a carboxylic acid.