Patent · US Expired

Hexa-cyclic compound

US5637770A · kind A · utility

5Cited by
2References
29Claims
0Family size

Assignees

Inventors

Key dates

Filing dateMay 31, 1995
Grant dateJun 10, 1997
Priority date
Expiry dateMay 31, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D495/22
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: ##STR1## The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-soluble, and has an excellent antitumour activity and a high degree of safety, and can be applied as an antitumour medicine for curing tumors of various kinds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.