Imidazole containing aminoboronic acids
US5639739A · kind A · utility
22Cited by
10References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 24, 1995 |
| Grant date | Jun 17, 1997 |
| Priority date | — |
| Expiry date | Mar 24, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates generally to .alpha.-aminoboronic acids and corresponding peptide analogs of the formula (I): ##STR1## in which the .alpha.-carbon is substituted with an optionally functionalized imidazole containing alkyl group. These compounds are useful as inhibitors of trypsin-like serine protease enzymes, especially thrombin, Factor X and Factor VII.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.