Oligothionucleotides
US5639873A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 4, 1994 |
| Grant date | Jun 17, 1997 |
| Priority date | — |
| Expiry date | Aug 4, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3531
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Chemical compounds consisting of an alpha or beta oligo-4'-thioribonucleotide or oligo-4'-thio-2'-deoxyribonucleotide characterized in that they comprise a concatenation of 4'-thioribonucleotides or 4'-thio-2'deoxyribonucleotides, respectively. The concatenation is optionally linked to an effector, in particular a radical corresponding to an intercalating agent or a photoactivatable or chemical radical, e.g. a radical carrying a function which reacts directly or indirectly with the nucleotide chains, or a radical whose presence enables easy and sensitive detection. Methods for preparing said compounds, and their uses in therapeutics, diagnostics and as laboratory reagents, are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.