One-pot process for the preparation of 3-quinolonecarboxylic acid derivatives

US5639886A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Rudolf Zerbes · Wuppertal, DE
• Paul Naab · Bad Reichenhall, DE
• Gerhard Franckowiak · Wuppertal, DE
• Herbert Diehl · Leverkusen, DE

Key dates

• Filing date: Dec 2, 1994
• Grant date: Jun 17, 1997
• Expiry date: Dec 2, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a one-pot process for the preparation of 7-heterocyclyl-substituted 3-quinolonecarboxylic acid derivatives. They possess a strong anti-microbial effect. They include active compounds such as, for example, ofloxacin, ciprofloxacin or enrofloxacin.