Monoclonal antibodies against Mycoplasma pneumoniae, hybridomas producing these, methods for the preparation thereof, and the use thereof

US5641638A · kind A · utility

Assignee

• Behringwerke Aktiengesellschaft · DE

Inventors

• Wolfgang Bredt · Glückstadt, DE
• Bernhard Gerstenecker · Albstadt, DE
• Enno Jacobs · Frankfurt am Main, DE
• Wilhelm Schuy · Obererbach, DE

Key dates

• Filing date: Jan 3, 1995
• Grant date: Jun 24, 1997
• Expiry date: Jan 3, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/975
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to monoclonal antibodies and fragments thereof which are specific for Mycoplasma pneumoniae P2 protein and have a cross-reactivity of 1% or less with five other species of the genus Mycoplasma and other pathogen species of the concomitant flora, and to methods for the preparation of the monoclonal antibodies according to the invention. The invention furthermore relates to hybridomas which produce the antibodies according to the invention, and to methods for the preparation thereof. Finally, the invention relates to the use of the monoclonal antibodies according to the invention for detecting Mycoplasma pneumoniae in a sample.