Modified bile acids process for their preparation and their use

US5641767A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Gunther Wess · Niederrodenbach, DE
• Alfons Ehnsen · Büttelborn, DE
• Werner Kramer · Schwandorf, DE
• Klaus Bock · Kelsterbach, DE

Key dates

• Filing date: Sep 12, 1995
• Grant date: Jun 24, 1997
• Expiry date: Sep 12, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J51/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to linker-modified bile acid derivatives of the formula I: ##STR1## wherein the radicals X.sup.1, X.sup.2, X.sup.3 and Y and n are as defined in the claims, and to a process for their preparation. The compounds according to the invention are therapeutically active and are thus suitable as drugs, especially as hypolipldemics. The invention further relates to the use of the bile acid derivatives according to the invention as drugs.