Benzoylguanidines substituted by heterocyclic N-oxide, process for their preparation and pharmaceutical compositions containing them

US5641792A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Heinz-Werner Kleemann · Bischofsheim, DE
• Hans-Jochen Lang · Hofheim, DE
• Jan-Robert Schwark · Frankfurt am Main, DE
• Andreas Weichert · Egelsbach, DE
• Wolfgang Scholz · Beverly, US
• Udo Albus · Florstadt, DE

Key dates

• Filing date: Sep 8, 1995
• Grant date: Jun 24, 1997
• Expiry date: Sep 8, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D215/60
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Benzoylguanidines substituted by heterocyclic N-oxide, process for their preparation, their use as a medicament or diagnostic agent, medicament containing them and intermediate products for their preparation Benzoylguanidines of the formula I ##STR1## with the meanings given in the text for the substituents, are described. These are compounds which have an outstanding activity on the cardiovascular system.