1H-indole-1-functional sPLA.sub.2 inhibitors
US5641800A · kind A · utility
36Cited by
10References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 13, 1995 |
| Grant date | Jun 24, 1997 |
| Priority date | — |
| Expiry date | Apr 13, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A class of novel 1H-indole-1-functional compounds is disclosed together with the use of such indole compounds for inhibiting sPLA.sub.2 mediated release of fatty acids for treatment of conditions such as septic shock. The compounds are 1H-indole-1-acetamides, 1H-indole-1-acetic acid hydrazides, and 1H-indole-1-glyoxylamides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.