Porphyrin, azaporphyrin, and related fluorescent dyes free of aggregation and serum binding
US5641878A · kind A · utility
51Cited by
16References
27Claims
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Key dates
| Filing date | Nov 2, 1994 |
| Grant date | Jun 24, 1997 |
| Priority date | — |
| Expiry date | Nov 2, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/19
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Fluorescent dyes which are free of aggregation and serum binding are provided. These dyes are suitable for applications such as fluorescence immunoassays, in vivo imaging and in vivo tumor therapy. The dyes are particularly useful in fluorescence immunoassays of biological samples containing serum. Such dyes have two polyoxyhydrocarbyl moities, one located on either side of a planar molecular structure such as a porphyrin derivative, azaporphyrin derivative, corrin derivative, sapphyrin derivative or porphycene derivative.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.