Patent · US Expired

System for dispensing pharmaceutically active compounds

US5642728A · kind A · utility

135Cited by

15References

4Claims

0Family size

Assignee

AB Astra · SE

Inventors

Jan Andersson · Erlangen, DE
Hans Jagfeldt · Lund, SE
Eva Trofast · Lund, SE
Kjell I. L. Wetterlin · Södra Sandby, SE

Key dates

Filing date	May 29, 1996
Grant date	Jul 1, 1997
Priority date	—
Expiry date	May 29, 2016

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K31/58
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method is provided for dispensing a clinically effective dose of an inhalable, pharmaceutically active compound. The method includes providing a dry powder inhaler containing a powder including the pharmaceutically active compound, and administering to a patient a dose of the compound that is less than 70% of the dose that would be necessary to obtain a physiologically equivalent result were the compound administered by a pressurized metered dose inhaler. The pharmaceutically active compound is in the form of primary particles at least 80% of which have a particle size of less than 10 microns, and the primary particles are provided as agglomerates which are deagglomerated during inhalation so that at least 40% of the dose administered is in the form of primary particles.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.