Autologous fibrin glue and methods for its preparation and use
US5643192A · kind A · utility
123Cited by
14References
15Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 6, 1995 |
| Grant date | Jul 1, 1997 |
| Priority date | — |
| Expiry date | Apr 6, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21005
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A fibrin glue includes a fibrinogen component and a thrombin component, both prepared from single donor plasma. The plasma is precipitated to produce a precipitate containing fibrinogen and a supernatant containing the thrombin. The precipitate may be resuspended in a small volume of supernatant and used as the fibrinogen component. The supernatant is further treated by clotting to convert residual fibrinogen to fibrin and filtration to remove the fibrin. The resulting serum can be used as the thrombin component.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.