Immunization by inoculation of DNA transcription unit
US5643578A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Jan 27, 1993 |
| Grant date | Jul 1, 1997 |
| Priority date | — |
| Expiry date | Jan 27, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to a method of immunizing a vertebrate, comprising introducing into the vertebrate a DNA transcription unit which comprises DNA encoding a desired antigen or antigens. The uptake of the DNA transcription unit by a host vertebrate results in the expression of the desired antigen or antigens, thereby eliciting humoral or cell-mediated immune responses or both humoral and cell-mediated responses. The elicited humoral and cell-mediated immune responses can provide protection against infection by pathogenic agents, provide an anti-tumor responses, or provide contraception. The host can be any vertebrate, avian or mammal, including humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.