Substrate useful for separating modified oligonucleotides
US5643717A · kind A · utility
2Cited by
9References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 16, 1993 |
| Grant date | Jul 1, 1997 |
| Priority date | — |
| Expiry date | Mar 16, 2013 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/44747
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is a substrate useful for separating unmodified and modified mononucleotides and oligonucleotides. The substrate includes at least 12% polymer in at least 50% (volume:volume) organic solvent, the organic solvent being a denaturing agent. This substrate is easily removable from the capillary using low pressure. Also provided is a method of separating unmodified and modified mononucleotides and oligonucleotides utilizing this substrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.