Merozoite proteins for use in detection of Babesia equi in horses using immunological techniques
US5643737A · kind A · utility
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2References
15Claims
0Family size
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Key dates
| Filing date | Mar 2, 1995 |
| Grant date | Jul 1, 1997 |
| Priority date | — |
| Expiry date | Mar 2, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/822
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a purified and isolated merozoite protein which is a specific indicator of infection by Babesia equi (B. equi) in horses. This protein contains a conserved region found in all strains of B. equi. It has a molecular weight of approximately 28 KDa and has been successfully purified and sequenced. The isolated and purified merozoite protein is used to prepare antibodies which can then be used in a competitive inhibition enzyme linked immunosorbent assay for the diagnosis of B. equi infection in horses.
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