Genes for the export of pertussis holotoxin
US5643747A · kind A · utility
5Cited by
1References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 31, 1994 |
| Grant date | Jul 1, 1997 |
| Priority date | — |
| Expiry date | Mar 31, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/235
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a cloned region of the Bordetella pertussis genome located 3' of the ptx operon encoding factors required for expression, assembly and secretion of pertussis holotoxin. Methods for obtaining increased levels of holotoxin production using homologous and heterologous hosts are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.