Systemic administration of esters and amides of antioxidants which may be used as antioxidant prodrug therapy for oxidative and inflammatory pathogenesis
US5643943A · kind A · utility
21Cited by
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16Claims
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Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Jul 1, 1997 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/72
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for treating vascular inflammatory pathologies are disclosed. Particularly, the methods utilize pharmaceutical compositions containing certain compounds having an anti-inflammatory and anti-oxidant moiety covalently linked by an amide or ester bond. The compounds are useful in preventing and treating inflammatory disorders through several mechanisms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.