Patent · US Expired

Method of making poly(propylene fumarate-coethylene oxide)

US5644005A · kind A · utility

8Cited by
2References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 24, 1996
Grant dateJul 1, 1997
Priority date
Expiry dateApr 24, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08L71/02
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A biodegradable block copolymer made from the transesterfication of a poly(propylene fumarate) prepolymer and a poly(ethylene oxide) prepolymer. The block copolymer poly(propylene fumarate -co- ethylene oxide) is capable of crosslinking at body temperature. Crosslinking requires an appropriate crosslinking monomer and an initiator. The biodegradable block copolymer has utility as a vascular implant became it can be injected as a fluid into the vascular system and crosslinked in situ.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.