Patent · US Expired

Vertebrate apoptosis gene: compositions and methods

US5646008A · kind A · utility

22Cited by
1References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 22, 1993
Grant dateJul 8, 1997
Priority date
Expiry dateJun 22, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K14/465
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The invention relates generally to compositions of and methods for obtaining and using a polypeptide other than BCL-2 that affects programmed vertebrate cell death. The invention relates as well to polynucleotides encoding those polypeptides, recombinant vectors carrying those sequences, the recombinant host cells including either the sequences or vectors, and recombinant polypeptides. The invention further provides methods for using the isolated, recombinant polypeptides in assays designed to select and improve substances capable of altering programmed cell death for use in diagnostic, drug design and therapeutic applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.