Cyclic peptide antifungal Agents
US5646111A · kind A · utility
16Cited by
4References
64Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 7, 1996 |
| Grant date | Jul 8, 1997 |
| Priority date | — |
| Expiry date | Mar 7, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I: ##STR1## wherein: R' is hydrogen, methyl or NH.sub.2 C(O)CH.sub.2 --; PA1 R" and R'" are independently methyl or hydrogen; PA1 R.sup.x1, R.sup.x2, R.sup.y1, R.sup.y2, R.sup.y3, and R.sup.y4 are independently hydroxy or hydrogen; PA1 R.sub.0 is a group of the formula ##STR2## R.sub.1 is C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, phenyl, p-halo-phenyl, p-nitrophenyl, phenoxy, benzyl, p-halo-benzyl, or p-nitro-benzyl; and PA1 R.sub.2 is an acyl side chain as defined herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.