Patent · US Expired

Peptide-based inhibitors of HIV replication

US5646120A · kind A · utility

26Cited by
8References
28Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 14, 1994
Grant dateJul 8, 1997
Priority date
Expiry dateDec 14, 2014

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Described herein are oligopeptides useful to inhibit replication in virally infected individuals. In a preferred embodiment of the invention, the oligopeptide is a D-arginine nonamer having N- and C-terminal protecting groups, which, at a 5 uM concentration, exhibits greater than 95% inhibition of HIV replication, in a standard assay.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.