Oxy-phenyl-(phenyl)glycinolamides with heterocyclic substituents

US5646162A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Ulrich Muller · Wuppertal, DE
• Richard Connell · Trumbull, US
• Siegfried Goldmann · Wuppertal, DE
• Klaus-Helmut Mohrs · Wuppertal, DE
• Siegfried Raddatz · Hanerau-Hademarschen, DE
• Michael Matzke · Wuppertal, DE
• Rudi Grutzmann · Solingen, DE
• Martin Beuck · Milford, US
• Stefan Wohlfeil · Hilden, DE
• Hilmar Bischoff · Wuppertal, DE
• Dirk Denzer · Wuppertal, DE

Key dates

• Filing date: Dec 1, 1995
• Grant date: Jul 8, 1997
• Expiry date: Dec 1, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Oxy-phenyl-(phenyl)gycinolamides with heterocyclic substituents are prepared by reaction of the corresponding oxyphenylcarboxylic acids with heterocyclic substituents with phenylglycinol. The new substances are suitable as active compounds in medicaments, in particular in agents having an antiatherosclerotic action.