Immunogens and the use thereof for obtaining antibodies against HBA.sub.1C

US5646255A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Christian Klein · Iffeldorf, DE
• Christa Hubner-Parajsz · Tutzing, DE
• Hans-Georg Batz · Tutzing, DE
• Wolfgang Rollinger · Polling, DE
• Ulrich Essig · Wissen, DE
• Lorenz Kerscher · Penzberg, DE

Key dates

• Filing date: Aug 15, 1994
• Grant date: Jul 8, 1997
• Expiry date: Aug 15, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Immunogens of formula I are provided for obtaining HbA.sub.1c -specific antibodies ##STR1## M is 1 to 40, T is a carrier protein and A is a 10-20 atoms spacer and is ##STR2## where X is S or --NH--, n is 1 to 4 and B is a succinimide containing organic radical. The antibodies obtained bind glycosylated hemoglobin to determine HbA.sub.1c in body fluids.