Antisense oligonucleotides against hepatitis B viral replication
US5646262A · kind A · utility
15Cited by
1References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 28, 1994 |
| Grant date | Jul 8, 1997 |
| Priority date | — |
| Expiry date | Jul 28, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/315
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antisense oligonucleotides that hybridize to segments of the preS1, S, C, and .epsilon. regions of the hepatitis B virus (HBV) RNA pregenome inhibit replication of the virus. Pharmaceutical compositions which contain these oligonucleotides as the active ingredients are effective against HBV infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.