Modified tumor cytotoxic factor (TCF) and DNA encoding such
US5648233A · kind A · utility
7Cited by
0References
11Claims
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Key dates
| Filing date | Sep 29, 1994 |
| Grant date | Jul 15, 1997 |
| Priority date | — |
| Expiry date | Sep 29, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Modified TCF in which one or more amino-acid residues of the wild type TCF responsible for glycosylation are substituted or deleted so that at least one N-linked oligosaccharide chain is removed. The modified TCFs have a longer biological half-lives without loss of their biological activities. The modified TCFs are therapeutically important as agents for liver diseases or as anti-cancer drugs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.