Peptides having bradykinin antagonist action

US5648333A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Stephan Henke · Bad Soden am Taunus, DE
• Hiristo Anagnostopulos · Wiesbaden, DE
• Gerhard Breipohl · Scheinfeld, DE
• Jochen Knolle · Kriftel, DE
• Jens Stechl · Frankfurt am Main, DE
• Bernward Scholkens · Kelkheim, DE
• Hans-Wolfram Fehlhaber · Idstein, DE
• Hermann Gerhards · Hofheim, DE
• Franz Hock · Dieburg, DE

Key dates

• Filing date: Jun 7, 1995
• Grant date: Jul 15, 1997
• Expiry date: Jun 7, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Peptides of the formula I EQU A-B-C-E-F-K-P-G-M-F'-I (I), wherein the terms A, B, C, E, F, K, P, G, M, F', and I are defined in the specification, have bradykinin antagonist action. Their therapeutic utility includes all pathological states which are mediated, caused or supported by bradykinin and bradykinin-related peptides.