Cloning and expression of neurocan, a chondroitin sulfate proteoglycan

US5648465A · kind A · utility

Assignees

• NEW YORK UNIVERSITY · US
• The Research Foundation of the State University of New York · US

Inventors

• Richard U. Margolis · New York, US
• Uwe Rauch · New York, US
• Renee K. Margolis · New York, US

Key dates

• Filing date: Nov 14, 1994
• Grant date: Jul 15, 1997
• Expiry date: Nov 14, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Novel eukaryotic neurocan polypeptides, derivatives and analogs thereof and nucleic acid encoding therefor, which are useful for providing soluble, biologically active heterologous proteins in hosts, as well as hosts transformed with this nucleic acid and methods for producing soluble heterologous proteins in hosts using such molecules, and therapeutic uses thereof.