Synthesis of reactive amorphous calcium phosphates
US5650176A · kind A · utility
90Cited by
21References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 29, 1995 |
| Grant date | Jul 22, 1997 |
| Priority date | — |
| Expiry date | Dec 29, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/926
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a novel process for converting a standard inert amorphous calcium phosphate precipitate into highly reactive amorphous solids. The amorphous solids can be used to react with other calcium phosphate solids to form a poorly-crystalline synthetic hydroxyapatite that provides both bioactivity and structural integrity. This novel amorphous material can be reacted with other calcium phosphates at or below 37.degree. C. to form a bone-like material consisting of poorly crystalline hydroxyapatite.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.