Fractionated polyalkylene oxide-conjugated hemoglobin solutions
US5650388A · kind A · utility
62Cited by
5References
51Claims
0Family size
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Key dates
| Filing date | Jun 30, 1995 |
| Grant date | Jul 22, 1997 |
| Priority date | — |
| Expiry date | Jun 30, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Polyalkylene oxide-conjugated hemoglobin solutions having a molecular weight greater than about 85,000 daltons and a degree of substitution of which substantially avoids clinically significant nephrotoxicity associated with hemoglobinuria in mammals. A method of simultaneously fractionating and purifying polyalkylene oxide-conjugated hemoglobins is al so disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.