Patent · US Expired

Use of DL-(+/-)-.alpha.-lipoic acid, D-(+)-.alpha.-lipoic acid, .alpha.-lipoic acid in reduced or oxidized form or salts for treating circulatory disorders

US5650429A · kind A · utility

16Cited by

1References

8Claims

0Family size

Assignee

Asta Medica Aktiengesellschaft · DE

Inventors

Frank Conrad
Hermann-August Henrich · Würzburg, DE
Wolfgang Geise · Dipbach, DE
Heinz Ulrich · Niedernberg, DE

Key dates

Filing date	Nov 8, 1995
Grant date	Jul 22, 1997
Priority date	—
Expiry date	Nov 8, 2015

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to the use of DL-(+/-)-.alpha. lipoic acid, D-(+)-.alpha.-lipoic acid, L-(-)-.alpha.-lipoic acid in reduced or oxidized form or of the metabolites and salts, esters, amides thereof for the preparation of medicines for the treatment of disorders caused by changes or disturbances in the rheological properties of the blood such as blood viscosity, erythrocyte flexibility and the aggregation of erythrocytes, in particular for the treatment of microangiopathy with disturbed microcirculation. It can also be used in the treatment of diabetics and of dialysis patients for protection of the erythrocytes, in central and peripheral circulatory disturbances and in tinnitus and hearing loss.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.