Substituted biphenyl derivatives

US5650444A · kind A · utility

Assignee

• Amerimas Home Products, Inc. · US

Inventors

• Thomas Joseph Caggiano · Levittown, US
• Joseph Prol, Jr. · West Chazy, US

Key dates

• Filing date: May 25, 1995
• Grant date: Jul 22, 1997
• Expiry date: May 25, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A compound of the following structure: ##STR1## wherein, when R.sub.8 =H: R.sub.1 =alkyl, cycloalkyl, arylalkyl, aryl; PA1 R.sub.2 =cycloalkyl, aryl, C.sub.3 -C.sub.10 alkyl; PA1 X,Y=O, S(O).sub.n, NH; PA1 Z=CHO, CO.sub.2 R.sub.3, CONHR.sub.4 R.sub.5, CN, COR.sub.6, H, halo, HCN, NHCONR.sub.4 R.sub.5, CONR.sub.4 OR.sub.5, CONR.sub.4 NR.sub.5 R.sub.6, 1-tetrazole, S(O).sub.n OH, S(O).sub.n NR.sub.3 R.sub.4, C.dbd.NOH, C(.dbd.N(OH)NH.sub.2, OCONR.sub.7 R.sub.6, P(O)(OR.sub.4).sub.2, C(.dbd.N(YR.sub.3))R.sub.4, NH.sub.2, SH, OH, OS(O).sub.2 R.sub.3, C(.dbd.NYC(.dbd.O)R.sub.3)R.sub.4, C(O)CO.sub.2 R.sub.3, C(O)CONR.sub.3 R.sub.4, CH(OH)CO.sub.2 R.sub.3, CHFCO.sub.2 R.sub.3, CF.sub.2 CO.sub.2 R.sub.3, CH(OH)CONR.sub.3 R.sub.4, CF.sub.2 CONR.sub.3 R.sub.4, C.dbd.NNH.sub.2, C(.dbd.NOC(.dbd.O)R.sub.3)R.sub.4, C(.dbd.NNHC(.dbd.O)R.sub.3)R.sub.4, C(.dbd.NOH)R.sub.3, C(.dbd.NNR.sub.3)R.sub.4, NHC(.dbd.O)R.sub.6 or C(O)CONH.sub.2 ; PA1 R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 =hydrogen, alkyl, aryl, aryalkyl, cycloalkyl, or fluoroalkyl; or a compound of Structure I, as just defined, wherein: PA1 X,Y=CH.sub.2, O, S(O).sub.n, or NH; PA1 Z and R.sub.8 =CO.sub.2 R.sub.3, CONR.sub.3, or R.sub.8 …